The following article was written in 2001 and slightly updated /
corrected over the next few years. Many aspects of it are now
very dated and it is retained as an historical insight to a different time
for transwomen. However this article was almost certainly the first
published in any media to suggest that the use of Domperidone might help
induce lactation in transwomen, which resulted in an on-line debate at the
time. In 2018 I was amused to read that a US clinic was claiming to
have made a major medical advance by using Domperidone to help stimulate
lactation in a transwoman.
The natural purpose of the female human breast is to provide sustenance and nourishment to babies. While almost all transsexual women proudly regard their breasts as an important sign of their femininity and womanhood, few really consider their biological purpose.
Some years ago an English newspaper published a story about a young woman breast-feeding her baby in a restaurant, she was asked to leave and wasn't at all happy about that. Not really headline material, but readers then discovered that the woman in question was a male-to-female transsexual. As a 'husband', she had begun female hormone treatment at about the same time as his/her wife had become pregnant. After the baby's birth, the transwoman had acupuncture to help kick-in her own milk production and was sharing nursing duties with her former wife. The story was inevitably intended to be rather sensationalist, but some transsexual women reading it were probably surprised to learn that their breasts might be capable of performing the function that they were intended for by nature.
The breasts of a transsexual woman are in fact quite capable of producing milk ("lactation") given the following circumstances:
One study of 27 genetic women who undertook a lactation induction programme found that 24 (89 percent) were successfully breast feeding well-nourished children. All 11 women who had never previously lactated were successful.
Whilst quite such a high success rate cannot be achieved with male-to-female transsexual women, there's no doubt that given a high degree of motivation combined with medication, support, and encouragement; lactation induction can often be successful in transsexual women.
With a breast that has been surgically enlarged with implants, the nipple may be more or less sensitive than normal. If the nerves around the areola were not cut or damaged during the surgery then it should still be possible to nurse fully or partially. Nerves are vital to breastfeeding since they trigger the brain to release prolactin and oxytocin, two hormones that affect milk production. The chances of breastfeeding also improve if the milk duct system is intact. It's impossible to know the full extent of damage — if any — until a woman tries to make and express milk. Once lactation starts, implants may also cause exaggerated breast engorgement with more intense than normal pain, fever, and chills.
The likelihood that implants cause serious lactation and milk production problems depends directly upon the kind of surgery had. Incisions that were made under the fold of the breast (inframammary) or through the armpit (transaxillary ) shouldn't cause any trouble. However, the popular periareolar method, making a "smile" incision around the areola, has greater risk of problems.
There's absolutely no evidence that silicone from silicone implants leaks into breast milk, but even if it did, it probably wouldn't harm a baby. Silicone is very similar to a substance used to treat a baby's stomach gas.
In order to be able to produce milk internally the breast must have certain structures in place, but fortunately these are present at birth in every human, whether genetically male or female. It's also worth noting that highly visible factors such as breast size and areola diameter that are often of great importance to transsexual women in fact have relatively little effect on the breasts potential ability to lactate and the quantity and quality of the milk that will be produced. Whatever the size of her breasts, a M2F transsexual woman can still potentially breastfeed if the internal structures are in place and undamaged.
Mammogenesis commences at puberty with the onset of oestrogen secretion by the ovaries, usually between the ages of 10 and 12 in the girl. Oestrogen causes enlargement of the mammary fat pad, one of the most oestrogen-sensitive tissues in the human body, as well as lengthening and branching of the mammary ducts. About 40% of male children also initiate mammary development during puberty due to the tendency of the testis to secrete significant quantities of oestrogens in early phases of its development. As testosterone secretion increases this function is lost.
Oestrogen stimulates breast growth by acting on the mammary tissue. With the onset of the menstrual cycle the presence of progesterone stimulates the partial development of mammary alveoli, so that by the age of 20 the mammary gland in the woman who has not been pregnant consists of a fat pad through which course 10 to 15 long branching ducts, terminating in grape-like bunches of mammary alveoli. In the absence of pregnancy the gland maintains this structure until menopause.
Mammogenesis is completed during pregnancy, with the gland becoming able to secrete milk sometime after mid-pregnancy.
Lactogenesis (referred to as the time when the milk "comes in") starts about 40 hours after birth of the infant and is largely complete within five days.
When nursing has ceased the gland undergoes partial involution, losing many of its milk producing cells and structures, a process which is only completed after menopause.
Development in the Transsexual Woman
The amount of hormone induced breast development achieved in the genetically XY male transsexual woman is very age dependent. Young boy-to-girls who start female treatment during their normal puberty years (i.e. about age 12-16) are likely to reach near normal breast development. But unfortunately the amount of development that can be expected rapidly tails off as the age of the commencement of hormone increases, and older transsexual women will commonly suffer from underdeveloped (hypoplastic) breasts.
Breast development is categorised by the "Tanner Stages" scale which goes from I to V. It can again be emphasized that there is really NO minimum degree of breast development in order to be able to lactate; there are well documented instances of even men with minimal Tanner I breasts producing some milk and breast feeding without using hormones. On the other hand there is no doubt that the higher the development stage, the easier it will usually be to start lactation and the greater the likely quantity of milk produced. In general, well developed Tanner IV or V type breasts are really required for successful nursing of a baby, perhaps a majority of the girls who start hormone treatment by age 25 are likely to achieve this but most older woman will achieve no more than Tanner III or even II breast development. Such hypoplastic breasts are very small or narrow, lack normal fullness, and may seem bulbous or swollen at the tip. They are also likely to be widely spaced and one breast may be larger than the other. Hypoplastic breasts don't develop and grow in response to any additional hormones given in order to simulate pregnancy and prepare the breast for lactation. Breasts of this kind have fewer milk glands than normal, leading to milk-production problems.
Breast Development During Pregnancy
It is necessary to understand how the human breast develops and prepares for milk production during a woman's pregnancy.
Mammogenesis is completed during pregnancy - indeed pregnancy is the period of greatest mammary growth. Extensive lobular and alveolar development occurs only during pregnancy, also milk secretory cells only develop during pregnancy, therefore this period is extremely important in determining the number of secretory cells in the lactating gland and the subsequent production of milk. Mammary growth (of the mother) accelerates throughout pregnancy and is fastest during the later stages of pregnancy, which coincides with the most rapid period of foetal growth.
Structure of a Pregnant Woman
But perhaps even more remarkable than this visible transformation are the extensive changes taking place inside her breasts, primarily under the stimulation of high levels of oestrogen and progesterone, combined with the rising levels of prolactin from the pituitary and human placental lactogen (HPL) from the placenta.
Nestled amid the breasts fat cells and glandular tissue is an intricate network of channels or canals called milk ducts. The additional hormones released during pregnancy cause the cells of the mammary fat pad to diminish in size and their place is taken by the developing ducts and alveoli.During the first three months of pregnancy the milk ducts increase in number and size; the ducts starting to branch off into smaller canals near the chest wall called ductules. During the mid-three months a cluster of small, grapelike, sacs called alveoli appear at the end of each ductule. A cluster of alveoli is called a lobule; a cluster of lobules is called a lobe. Each breast contains between 15 and 20 lobes, with one milk duct for every lobe. During the last three months of pregnancy the alveoli grow and mature.
Milk is produced inside the alveoli, which are surrounded by tiny muscles that squeeze the glands and push milk out into the ductules. Those ductules lead to a bigger duct that widens into a milk pool or milk sinus directly beneath the areola. Milk pools (also known as sinus) act as reservoirs that hold milk until a baby suckles it through tiny openings in the nipple. Essentially the 15 or 20 milk ducts act as individual straws that all end at the tip of the nipple and deliver milk into a baby's mouth.
The mammary gland becomes able to secrete milk sometime after mid-pregnancy, and begins to produce small amounts of a protein- and fat-rich secretion sometimes referred to as precolostrum. It seems likely that mammary development continues through the duration of pregnancy since milk secretion by mothers of premature infants often appears to be diminished. The onset of copious milk secretion (or lactogenesis) is held in check by the high levels of circulating progesterone until after child birth.
Differentiation of the breast to its mature status occurs by the third month of pregnancy, although it will take about 6 months for the breast system to fully develop and become functional for lactation. Indeed, mammary growth will continue right up to birth, and even after if nursing. In a pregnant woman, by time the baby is born, glandular tissue has replaced most of the fat cells and accounts for the much enlarged breast. The increase in size varies greatly with the individual, ranging from zero to 800 cc of volume (and 1½ lb of weight!) per breast; the average being about 400 cc. It is normal for women to increase by one or two cup sizes during pregnancy, although this will decline (sometimes dramatically) after the cessation of lactation.
Oestrogen and Progesterone
Oestrogen and progesterone together establish the conditions needed for geometric cell multiplication to occur. For example, from one original cell, 8 cell divisions yields 128 cells.
During pregnancy, the mammary tissue has oestrogen receptors and progesterone receptors. During lactation the mammary gland has oestrogen receptors, but not progesterone receptors.
Prolactin is a protein hormone secreted from the anterior pituitary gland, as well as assisting in breast development; it stimulates and controls the actual production of milk.
In a pregnant woman, the placenta produces an important hormone called Human Placental Lactogen (HPL) which adjusts the maternal metabolism. One of its functions is similar to prolactin, i.e. stimulation of milk production by the mammary glands. HPL seems to work with oestrogen and progesterone to increase the number of alveoli in mammary glands and also plays a role in making the alveoli functional (capable of producing milk). It's thought that the level of HPL hormone activity in the maternal blood regulates the extent of mammary development during late pregnancy. HPL also causes the secretion of a form of milk called colostrum from about the fifth month of pregnancy.
Yet another, and apparently unimportant, hormone is secreted by the pituitary gland of a pregnant woman, Melanocyte Stimulating Hormone (MSH). Its only known effect is to stimulate the skin to produce pigmentation, causing the aeroli to enlarge and darken.
Milk Production in a Maternal Mother
Lactogenesis is associated with an abrupt increase in milk volume secretion, which goes from a mean of about 50 ml per day on day 2 of lactation to about 500 ml per day on day 4. After this time there is a gradual volume increase to about 850 ml/day by three months postpartum. There are also profound changes in milk composition during the early post child birth period as the production of milk products comes into high gear. By 10 days after child birth the milk has assumed the composition characteristic of mature milk. There are minor composition changes that continue throughout lactation. Full lactation, or the secretion of mature milk, continues as long as the demand is there, up to three to four years for infants in some cultures.
Three factors are necessary for successful lactogenesis: a developed mammary gland, continued high plasma prolactin levels, and a fall in progesterone and oestrogen levels that otherwise inhibit lactation - it can therefore be partially inhibited by high doses of oestrogen. It is important to note that the milk "comes in" at the same rate whether the infant suckles during the first 48 hours or not. Thus the onset of milk secretion depends, not on milk removal from the breast, but on the changes in hormonal status associated with child birth. However, continued milk secretion depends on milk removal from the breast, the involutional process sets in after only 3 to 4 days if breast-feeding is not initiated.
Breast Stimulation in the Transsexual Woman
It is appropriate at this point to distinguish between trying to achieve some slight lactation, ranging from a few drops up to as much as 35% that of a nursing mother, and trying to achieve full and copious milk production as the primary sorice of nutrient for a baby. Both require some degree of hormonal stimulation, but it's a case of for how long, and also how well the breasts respond to the hormonal stimulation.
If only a minimal degree of lactation is being attempted then the high oestrogen regimen may be as short as two weeks. But if full lactation is desired, then the transsexual woman must try to induce all the necessary developmental changes in her breasts by simulating a full period pregnancy by taking high doses of oestrogen and progesterone hormones for a period of at least six months (probably not coincidently, a premature baby born after the 28th week or sixth month of pregnancy is "viable" and will often survive, and will thus require feeding). This sustained hormone treatment may stimulate her breast in to developing and preparing for lactation, but unfortunately transsexual women with underdeveloped hypoplastic breasts are unlikely to succeed in this endeavour as their breasts will fail to respond to the additional hormones.
Also, in a pregnant woman her production of the estriol type of oestrogen greatly increases and it becomes the dominant type of oestrogen in her body. When present in high levels (unlike the non-pregnant lower levels), one of its effects is to help prepare the breast for milk production. However, the "weak" estriol oestrogen is rarely taken by transsexual women as part of their hormone therapy, instead standard oestrogen prescriptions are either of the estradiol (e.g. the Estrace brand) or estrone (e.g. the popular Premarin brand) types. Unfortunately, prolonged taking of large doses of these "strong" oestrogen types, as is common with transsexual women, seems to de-sensitise the body to estriol, making stimulating the breast to prepare for lactation via hormones much more difficult.
Assuming that the hormones have an effect, the period of the most visible breast growth is often during the first eight weeks of treatment. This enlargement is potentially just temporary as it's primarily due to engorgement of the blood vessels, enabling increased circulation to the breasts. Thereafter, oestrogen hormones stimulate cell mitosis and growth of the ductal system, the development and differentiation of the glandular tissue (lobules and alveoli) is dependent on progesterone, whilst breast fat accretion seems to require both.
Regarding other hormones found in pregnant woman:
Most genetic women and some men can induce lactation to some extent with only mechanical stimulation. This consists of breast massage, nipple manipulation, and sucking - the later either by a baby or by expressing using a good quality electric breast pump with a double pump kit. Realistically expression by hand, or even with a hand pump, is simply not a practical alternative to an electric double breast pump given the frequent and prolonged sucking required on each breast.
A possible expressing regime: Begin by expressing each breast for about five minutes, three times a day. Increase the length of the pumping session as you become more comfortable, until you are expressing for a total of about 15 to 20 minutes on each breast every two to three hours during the day. Expressing both breasts simultaneously by double-pumping obviously saves a lot of time every day by this point! You must include night time pumping sessions, allowing just one long 4-5 hours period of sleep.Constant expressing will soon get to become hard work, when after a week you still haven't seen any milk at all, try not to become discouraged or concerned, unfortunately it may well take four to six weeks for the breasts to begin producing milk this way. Some dedicated women have reported only finally achieving some success after two or three months pumping!
Stress, tension, and fatigue all produce hormones that can reduce let-down. Avoid smoking and excessive alcohol and caffeine - these are known to inhibit a mother's milk production and let-down.
In order to pump effectively and increase milk supply it is essential to relax and stimulate as much as possible the milk let-down response crucial to milk expression. Suitable mental or environmental stimuli such as baby photo's, imagining yourself breast feeding, direct sucking stimulation of the nipples and immediately surrounding tissue, playing a tape of the cries of a hungry baby, ... etc, are essential aids to milk production. And a partner can greatly assist with sexually arousing mental stimulation and manual manipulation of the woman's body before, and even during, her expression period.
It is essential to establish a routine to both start and then maintain lactation. For example begin by expressing each breast for about five minutes, three times a day. Increase the length of the pumping session as you become more comfortable, until you are expressing for a total of about 15 to 20 minutes on each breast every two to three hours during the day. Expressing both breasts simultaneously by double-pumping obviously saves a lot of time every day by this point! You must include night time pumping sessions, allowing just one long 4-5 hours period of sleep.
Here are some tips to help both manual and mechanical expression:
Achieving Milk Production in the Transsexual Woman
point mechanical breast stimulation, particularly sucking (with
a breast pump or by a baby) should be started and an oxytocin
nasal spray used to stimulate milk release. If not already
begun a course of a prolactin enhancing drug
such as domperidone (brand name Motilium) is highly
recommended to help milk production. [Although the US
Federal Drug Administration
warns against using the anti-nausea drug for this purpose.]
Success is not guaranteed, but some milk production can be
expected in a majority of cases. Milk production typically begins
between 1-4 weeks after initiating stimulation using prolactin enhancing
drugs, although it can be as little as 2-3 days if hormones were taken and
were effective, or as long as 4-6 weeks if relying purely on mechanical
One study of induced lactation using enhancing medications
describes the onset of milk production being between 5-13 days. At
first, the woman may see only drops. During the time that milk
production is building, women may notice changes in the colour of the
nipples and areolar tissue. Breasts may become tender and fuller.
Some women report increased thirst, and changes in their menstrual cycle or
As the body readies itself for lactation, it pumps extra blood into the
alveoli, making the breasts firm and full. Swollen blood vessels,
combined with an abundance of milk, may make the breasts temporarily painful
and engorged, but nursing or expressing frequently in the first few days
will help relieve any discomfort.
Milk Release When
oxytocin reaches the breast it causes the tiny muscles around
the milk-filled alveoli to contract and squeeze. The milk
is emptied into the ducts, which transport it to the milk pools
just below the areola. When s/he suckles, the nursing
infant presses the milk from the pools into his mouth, both
manual and mechanical expression techniques can simulate this to
a reasonable degree.
the milk flow increases, the lactating woman may feel some tingling,
stinging, burning, or prickling in her breasts. The milk may drip or
even spray during let-down.
of oxytocin is that it the nursing woman may feel calm,
satisfied, and even joyful as she nurses or expresses.
Maintaining Lactation The
volume of milk produced is primarily a function of demand and is
unaffected by maternal factors such as nutrition or age. Not a lot
of milk will be produced unless suckling (natural or artificial) is
frequent and consistent, the milk itself contains an inhibitor of milk
production that builds up if the milk remains in the mammary gland for a
prolonged period of time. Adequate milk removal from the breast is
absolutely necessary for continued milk production.
nursing an infant is not immediately and regularly possible then in
order to maintain milk flow it will be necessary to artificially
stimulate let-down by expression using a breast pump. Two
hormones are necessary for this continued production: oxytocin
and prolactin. As mentioned above, oxytocin is necessary
for the milk ejection reflex that extrudes milk from the
alveolar lumen. Prolactin is necessary for continued milk
production by the mammary alveoli. The secretion of both
hormones is promoted by the afferent nerve impulses sent to the
hypothalamus by the process of suckling. However, whereas
the secretion of oxytocin is highly influenced by the activity
of higher brain centres, prolactin secretion appears to be
determined primarily by the strength and duration of the
suckling stimulus. Although prolactin levels fall with
prolonged lactation, at least some basal level appears to be
necessary for continued milk production. There appears to
be no direct relation between prolactin levels and milk
production and therefore it is thought that the rate of milk
production depends on control mechanisms localized within the
Using a SNS
Nutritional Value of Induced Milk
Success is not guaranteed, but some milk production can be expected in a majority of cases. Milk production typically begins between 1-4 weeks after initiating stimulation using prolactin enhancing drugs, although it can be as little as 2-3 days if hormones were taken and were effective, or as long as 4-6 weeks if relying purely on mechanical stimulation.
One study of induced lactation using enhancing medications describes the onset of milk production being between 5-13 days. At first, the woman may see only drops. During the time that milk production is building, women may notice changes in the colour of the nipples and areolar tissue. Breasts may become tender and fuller. Some women report increased thirst, and changes in their menstrual cycle or libido.
As the body readies itself for lactation, it pumps extra blood into the
alveoli, making the breasts firm and full. Swollen blood vessels,
combined with an abundance of milk, may make the breasts temporarily painful
and engorged, but nursing or expressing frequently in the first few days
will help relieve any discomfort.
When oxytocin reaches the breast it causes the tiny muscles around the milk-filled alveoli to contract and squeeze. The milk is emptied into the ducts, which transport it to the milk pools just below the areola. When s/he suckles, the nursing infant presses the milk from the pools into his mouth, both manual and mechanical expression techniques can simulate this to a reasonable degree.
As the milk flow increases, the lactating woman may feel some tingling, stinging, burning, or prickling in her breasts. The milk may drip or even spray during let-down.
A benefit of oxytocin is that it the nursing woman may feel calm, satisfied, and even joyful as she nurses or expresses.
The volume of milk produced is primarily a function of demand and is unaffected by maternal factors such as nutrition or age. Not a lot of milk will be produced unless suckling (natural or artificial) is frequent and consistent, the milk itself contains an inhibitor of milk production that builds up if the milk remains in the mammary gland for a prolonged period of time. Adequate milk removal from the breast is absolutely necessary for continued milk production.
If nursing an infant is not immediately and regularly possible then in order to maintain milk flow it will be necessary to artificially stimulate let-down by expression using a breast pump.The more you nurse or express, the more milk that will be produced - nursing 10 to 15 minutes per breast every 2-3 hours (day and night!) is optimum! Expressing less than once every 5-8 hours, will result in dramatically less milk production, although some milk production will continue so long as an infant is suckled or milk is expressed at least twice per day. Less than that will result in complete cessation of milk production within one to three weeks. But with sufficient and regular stimulation, it is quite possible to maintain lactation for months, even years.
Two hormones are necessary for this continued production: oxytocin and prolactin. As mentioned above, oxytocin is necessary for the milk ejection reflex that extrudes milk from the alveolar lumen. Prolactin is necessary for continued milk production by the mammary alveoli. The secretion of both hormones is promoted by the afferent nerve impulses sent to the hypothalamus by the process of suckling. However, whereas the secretion of oxytocin is highly influenced by the activity of higher brain centres, prolactin secretion appears to be determined primarily by the strength and duration of the suckling stimulus. Although prolactin levels fall with prolonged lactation, at least some basal level appears to be necessary for continued milk production. There appears to be no direct relation between prolactin levels and milk production and therefore it is thought that the rate of milk production depends on control mechanisms localized within the mammary gland.
Using a SNS
Nutritional Value of Induced MilkMilk released by a mother during the first few days of lactation after giving birth is called colostrum; it is richer in proteins, minerals, and immunoglobulins and is lower in calories and fat than the mature milk that develops over the following few weeks. The level of fats, lactose, and B vitamins gradually increases in breast milk during the first month of lactation. Mature breast milk is rich in the mother's white blood cells and hormones and substances such as immunoglobulins, which protect the infant against bacteria and other infectious agents.
The milk brought in by inducement skips the colostral phase, instead it more closely resembles transitional and mature breast milk. It is thus not ideal for new-born babies, but studies of non-maternal women nursing after induced lactation indicate that that their infants are well-nourished. However, it must be noted that many women felt they were only providing about 50-70% of the nutrition their babies needed with breast milk alone. If a transsexual woman is nursing it is therefore also very likely that she will be able to produce only a portion of the breast milk the baby needs, and it will be necessary to boost the baby's milk intake with formula. For this a Supplemental Nursing System (SNS) is valuable alternative to the traditional bottle. The device consists of a plastic pouch to hold breast milk or formula and attached thin, flexible tubes that run down each breast to the nipple. Since the baby takes both nipple and tube into his mouth when he suckles, he benefits from all the breast milk that is available.
Breast Feeding by Transwomen
The number of transwomen adopting babies, or having a baby via a surrogate mother other or complex arrangement is increasingly dramatically. In some instances the transwoman is technically the baby's father as her sperm was used to impregnate an egg.
There are now numerous cases where a baby's 'mother' from its birth is a transwomen. Many want to breast feed, but can't. However a close approximation to breast feeding - for both the baby and the mother - can be achieved using a Supplemental Nursing System (SNS).
Achieving lactation is a challenge for MTF transsexuals (do you early want to wake up at 3:00 am to use a breast pump?), but it is quite possible as indicated at the start of this article for a transwoman to breast feed a baby.
In 2010 the Oprah Winfrey programme featured Dr Christine McGinn - the "Mum who fathered who own children". Christine is a lesbian MTF transsexual woman, before SRS she had a sperm sample frozen and this was used for an IVF procedure which happily resulted in her female partner giving birth to twins. Christine was able to breastfeed to the babies, she says:
In January 2018 Transgender Health published a case study by Zil Goldstein, and Dr. Tamar Reisman of the Mount Sinai Center for Transgender Medicine and Surgery in New York. This describes how a 30-year old transgender woman approached Reisman and Goldstein at their clinic - "the woman was pleasant, well-nourished, and her breasts were well-developed". They learnt that her partner was pregnant but didn't want to breastfeed, and that she was hoping to take on the role. The clinic then conducted probably the first professionally supervised medical study in to induced lactation in a transgender woman. The unnamed patient was able to achieve sufficient breast milk volume to be the sole source of nourishment for her child for 6 weeks after birth. Her treatment essentially followed the basic framework already described for induced lactation:
Key points of the study include:
The study proves that functional lactation can be
induced in a transgender women - and the "ground-breaking" approach is
extra-ordinarily similar to that first suggested by this website (see
below) back in 2001 - including the then unheard of use of domperidone.
The bad news is that however is that despite the patient having
unusually good breast development and excellent medical support, she was
unable to satisfactorily breast feed the baby for the 4-6 months
required until weaning can began. This is a disappointing
precedence for other young transwomen.
Is it worth it?
That of course depends upon yourself and your objectives. Hundreds of hours of effort, a considerable amount of money spent on pumps and drugs, and an enormous amount of will power is a non-trivial investment.
Many transwomen claim to have succeeded in secreting a milk-like fluid from their breasts, and for most that seems to a key goal achieved. But in my mind, by far the best objective ever possible is to breast feed your own baby. Here's some inspiring words I received in 2016 from a 29 year old transwoman, newly married and with an adopted baby:
The happy mother is very probably the same woman featured in the Transgender Health case study described earlier.
Lactation Enhancing Drugs
Another related but older medication is metoclopramide (brandnames Maxeran and Reglan), this is also known to increase milk production but it has frequent side effects which have made its use for many nursing mothers unacceptable (fatigue, irritability, depression). But in general domperidone is much preferable; it has fewer side effects because it does not enter the brain tissue in significant amounts.
Genetic women trying to start lactation are advised that prolactin enhancing drugs need only be started only after the ending of any oestrogen treatment as oestrogen, particularly those types found in contraceptive pills, retard the start of lactation. However many transsexual women seem to gain considerable benefits from the breast developing effects of prolactin even if it's not initiating lactation because of their high oestrogen intake, and thus should not be deterred from early use.
In many countries domperidone tablets are available without prescription. Generally, start at 20 milligram's (two 10 mg tablets) four times a day, i.e. about every 6 hours. After starting domperidone, it may take three or four days before any effect is noticed, though sometimes women notice an effect within 24 hours. It appears to take two to three weeks to get a maximum effect. Most women take domperidone for 3 to 8 weeks, but women who are nursing adopted babies usually take the drug continuously in order to maintain lactation.
Unfortunately Motilium is not yet available in the USA so domperidone may have to be used instead - usually just for 4 weeks rather than continuously. Also, in rare cases Motilium may cause stomach or digestive upsets and so domperidone may be preferred.
Some women find that herbal seed capsules such Blessed Thistle and Fenugreek help increase their lactation, and these are very commonly taken.
Some "morning sickness" and nausea is very probable at first, if more severe side effects are experienced then medical help should be sought immediately. Long term use of such high dosage levels should be avoided, and if it's clear that no beneficial effects are occurring within 6-8 weeks then the regimen should be abandoned and the previous hormone regimen reverted to.
"Attempted lactogensis" means reverting to the prior hormonal regimen in order stimulate the start of milk production and lactation, this must involve a considerable reduction in oestrogen and progesterone hormone intake, in pre-SRS women it may actually require a reduction to less than their normal regimen. If a baby is to be nursed then medical advice should be sought as to what hormones can still be safely taken and in what dosage, and any anti-androgens being taken must be stopped. Prolactin-enhancing drugs should continue to be taken, e.g. 2 Motilium tablets every 6 hours, each containing 10 mg domperidone maleate.
Antiandrogens may also be helpful to a pre-SRS transsexual women trying to induce lactation, although they should never be taken by a pregnant woman, or subsequently if breast feeding. The most commonly used antiandrogens are spironolactone (brand name Aldactone), flutamide (Eulexin) and cyproterone acetate (Androcur). Spironolactone, in a dosage of 25 to 100 mg administered twice daily, is the most commonly used antiandrogen because of its safety, availability and low cost. Flutamide is usually given in a dosage of 250 mg twice daily, and cyproterone is given in a dosage of 25 to 50 mg per day. Pre-SRS women may well already be taking much higher dosages of antiandrogens and these should not be increased - indeed in some cases it may be advisable to change the drug or reduce the dosage to the levels given here.
NursingThe female hormones taken by transsexual women induce breast development ranging from the slight to full. Typically their breasts appear unsatisfactorily small and about 50% of transsexual women have breast augmentations. However even very small breasts - particularly those of women who begin hormones before their 30's - can often function as nature intended, i.e. feed a baby.
Breast augmentation, common in transsexual women, does not normally prevent breast feeding. The main reason that breastfeeding may not be recommended or encouraged by the physician is if the drugs and other hormones being taken may make the milk unsuitable for nursing.
Once the baby is born, the transsexual mother may well be able to experience the final physical act of pregnancy and birth and attempt to nurse her new baby - albeit with many assumptions such as being well enough after the delivery and her breasts are adequately developed and haven't been badly damaged by augmentation. There are already a few instances of transsexual women lactating and even breast feeding the babies of ex-wives or female partners.
Breastfeeding normally strongly recommended by doctors, it is by far and away the best and most convenient way to feed a baby. Not only will the baby be healthier, but it also helps the new mother lose weight more easily. Calories are burned during milk production; indeed some of the weight gained by a woman during pregnancy is intended to be used during lactation.Breastfeeding also releases a hormone in the woman's body that acts as a natural tranquillizer, filling the mother with a sense of calm and well-being while she is breastfeeding.
If you don't have a baby or young child to nurse then hiring or buying a good quality, fully automated, electric breast pump that closely imitates the natural rate and rhythm of a baby's suck pattern is essential in order to regularly artificially stimulate let-down and express milk. Some automatic pumps can "double pump" (i.e. pump both breasts at once) thereby increasing prolactin levels and milk production while at the same time decreasing the amount of time a pumping session takes by about half to about 15 minutes.
A good quality electrical pump with a double pumping capability is simply essential. The best option is a hospital grade breast pump such as the "large" Medela (Classic) or the Ameda-Egnel Elite, unlike cheaper pumps these test and regulate pressure; they cost perhaps $40-$50 a month to rent. If you have problems finding a rental agent then try contacting the LeLeche League for help.
If you want to actually buy your pump, then a popular high-end option is the Medela Lactina at perhaps $500 (it can also often be rented for about $30-35 a month), while one entry level option is the Medela Pump-in-Style for around $300. Remember to get the double pump kit and accessories.
However it may be worth having a manual breast pump as well the electrical. The big advantage of a manual pump is that being light and small it can be conveniently carried in your bag when you know that you will be unable to meet a scheduled session on your electrical pump. If you are working, 30 minutes hidden in the toilets at lunch time using a hand pump may be the only option if the alternative is going more than about 6 hours without pumping. And a whole day without pumping might undo months of hard work and take you back to nearly the beginning! Because hand-pumps are cheap, it's possible to buy a couple of different models and experiment to find the one that is most comfortable, gives the best fit and suction to your breasts, is the most comfortable in the hand, and is the least tiring to use.
Inducing and maintaining lactation requires:
La Leche League International publishes the useful booklet "Nursing the Adopted Baby"
Information on lactation inducement can be found at The Adoptive Breastfeeding Resource Website
Some very interesting information and protocols for induced lactation can be found at Asklenore.info
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